Sunday, December 30, 2012

155213-67-5 | Ritonavir




Name: Ritonavir
Descriptions:
Product Number LS50034
CAS Number 155213-67-5
Product Name Ritonavir
Molecular Formula C37H48N6O5S2
Formula Weight 720.94
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Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS. It is now rarely used for its own antiviral activity, but remains widely used as a booster of other protease inhibitors. More specifically, ritonavir is used to inhibit a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4). The drug’s molecular structure inhibits CYP3A4, so a low dose can be used to enhance other protease inhibitors. This discovery has drastically reduced the adverse effects and improved the efficacy of PI’s and HAART. 
Synonyms  Norvir, Norvir Softgel