Thursday, January 31, 2013

7782-26-5 | (R)-(-)-2-Phenylpropionic acid




Name: (R)-(-)-2-Phenylpropionic acid
Descriptions:
Product Number LS30098
CAS Number 7782-26-5
Product Name (R)-(-)-2-Phenylpropionic acid
Molecular Formula C9H10O2
Formula Weight 150.17
http://www.lakesyn.com/html/e_1074.html

For price inquiry, please send us email: sales@lakesyn.com

62961-64-2 | Diisopropyl D-tartrate




Name: Diisopropyl D-tartrate
Descriptions:
Product Number LS30097
CAS Number 62961-64-2
Product Name Diisopropyl D-tartrate
Molecular Formula C10H18O6
Formula Weight 234.25
http://www.lakesyn.com/html/e_1058.html

For price inquiry, please send us email: sales@lakesyn.com

497-09-6 | L-Glyceraldehyde




Name: L-Glyceraldehyde
Descriptions:
Product Number LS30096
CAS Number 497-09-6
Product Name L-Glyceraldehyde
Molecular Formula C3H6O3
Formula Weight 90.08
http://www.lakesyn.com/html/e_1049.html

For price inquiry, please send us email: sales@lakesyn.com

2018-61-3 | N-Acetyl-L-phenylalanine




Name: N-Acetyl-L-phenylalanine
Descriptions:
Product Number LS30095
CAS Number 2018-61-3
Product Name N-Acetyl-L-phenylalanine
Molecular Formula C11H13NO3
Formula Weight 207.23
http://www.lakesyn.com/html/e_1048.html

For price inquiry, please send us email: sales@lakesyn.com

20312-36-1 | L(-)-3-Phenyllactic acid




Name: L(-)-3-Phenyllactic acid
Descriptions:
Product Number LS30094
CAS Number 20312-36-1
Product Name L(-)-3-Phenyllactic acid
Molecular Formula C9H10O3
Formula Weight 166.17
http://www.lakesyn.com/html/e_1046.html

For price inquiry, please send us email: sales@lakesyn.com

51019-43-3 | (R)-(-)-alpha-acetoxyphenylacetic acid




Name: (R)-(-)-alpha-acetoxyphenylacetic acid
Descriptions:
Product Number LS30093
CAS Number 51019-43-3
Product Name (R)-(-)-alpha-acetoxyphenylacetic acid
Molecular Formula C10H10O4
Formula Weight 194.18
http://www.lakesyn.com/html/e_1020.html

For price inquiry, please send us email: sales@lakesyn.com

90719-32-7 | (S)-4-Benzyl-2-oxazolidinone




Name: (S)-4-Benzyl-2-oxazolidinone
Descriptions:
Product Number LS30092
CAS Number 90719-32-7
Product Name (S)-4-Benzyl-2-oxazolidinone
Molecular Formula C10H11NO2
Formula Weight 177.20
http://www.lakesyn.com/html/e_1012.html

For price inquiry, please send us email: sales@lakesyn.com

Monday, January 28, 2013

78508-96-0 | (S)-(-)-5-(Hydroxymethyl)-2(5H)-furanone




Name: (S)-(-)-5-(Hydroxymethyl)-2(5H)-furanone
Descriptions:
Product Number LS30091
CAS Number 78508-96-0
Product Name (S)-(-)-5-(Hydroxymethyl)-2(5H)-furanone
Molecular Formula C5H6O3
Formula Weight 114.10
http://www.lakesyn.com/html/e_1003.html

For price inquiry, please send us email: sales@lakesyn.com

130798-48-0 | (R)-Di-2-Naphthylprolinol




Name: (R)-Di-2-Naphthylprolinol
Descriptions:
Product Number LS30090
CAS Number 130798-48-0
Product Name (R)-Di-2-Naphthylprolinol
Molecular Formula C25H23NO
Formula Weight 353.46
http://www.lakesyn.com/html/e_1002.html

For price inquiry, please send us email: sales@lakesyn.com

118399-28-3 | (R)-Benzyl-5-oxo-tetrahydro-furan-3-ylcarbamate




Name: (R)-Benzyl-5-oxo-tetrahydro-furan-3-ylcarbamate
Descriptions:
Product Number LS30089
CAS Number 118399-28-3
Product Name (R)-Benzyl-5-oxo-tetrahydro-furan-3-ylcarbamate
Molecular Formula C12H13NO4
Formula Weight 235.24
http://www.lakesyn.com/html/e_997.html

For price inquiry, please send us email: sales@lakesyn.com

87219-29-2 | Benzyl (S)-(-)-tetrahydro-5-oxo-3-furanylcarbamate




Name: Benzyl (S)-(-)-tetrahydro-5-oxo-3-furanylcarbamate
Descriptions:
Product Number LS30088
CAS Number 87219-29-2
Product Name Benzyl (S)-(-)-tetrahydro-5-oxo-3-furanylcarbamate
Molecular Formula C12H13NO4
Formula Weight 235.24
http://www.lakesyn.com/html/e_996.html

For price inquiry, please send us email: sales@lakesyn.com

71607-32-4 | Di-p-toluoyl-D-tartaric acid monohydrate




Name: Di-p-toluoyl-D-tartaric acid monohydrate
Descriptions:
Product Number LS30087
CAS Number 71607-32-4
Product Name Di-p-toluoyl-D-tartaric acid monohydrate
Molecular Formula C20H18O8.H2O
Formula Weight 404.37
http://www.lakesyn.com/html/e_978.html

For price inquiry, please send us email: sales@lakesyn.com

71607-31-3 | Di-p-toluoyl-L-tartaric acid monohydrate




Name: Di-p-toluoyl-L-tartaric acid monohydrate
Descriptions:
Product Number LS30086
CAS Number 71607-31-3
Product Name Di-p-toluoyl-L-tartaric acid monohydrate
Molecular Formula C20H18O8.H2O
Formula Weight 404.37
http://www.lakesyn.com/html/e_977.html

For price inquiry, please send us email: sales@lakesyn.com

Sunday, January 27, 2013

5402-60-8 | 2,6-Dimethylbenzylchloride




Name: 2,6-Dimethylbenzylchloride
Descriptions:
Product Number LS10100
CAS Number 5402-60-8
Product Name 2,6-Dimethylbenzylchloride
Molecular Formula C9H11Cl
Formula Weight 154.64
http://www.lakesyn.com/html/e_269.html

For price inquiry, please send us email: sales@lakesyn.com

18638-99-8 | 3,4,5-Trimethoxybenzylamine




Name: 3,4,5-Trimethoxybenzylamine
Descriptions:
Product Number LS10099
CAS Number 18638-99-8
Product Name 3,4,5-Trimethoxybenzylamine
Molecular Formula C10H15NO3
Formula Weight 197.23
http://www.lakesyn.com/html/e_265.html

For price inquiry, please send us email: sales@lakesyn.com

945971-14-2 | 2-bromo-3-fluoro-5-nitrophenol




Name: 2-bromo-3-fluoro-5-nitrophenol
Descriptions:
Product Number LS10098
CAS Number 945971-14-2
Product Name 2-bromo-3-fluoro-5-nitrophenol
Molecular Formula C6H3BrFNO3
Formula Weight 236.00
http://www.lakesyn.com/html/e_263.html

For price inquiry, please send us email: sales@lakesyn.com

1140-17-6 | 2-Amino-4'-bromobenzophenone




Name: 2-Amino-4'-bromobenzophenone
Descriptions:
Product Number LS10097
CAS Number 1140-17-6
Product Name 2-Amino-4'-bromobenzophenone
Molecular Formula C13H10BrNO
Formula Weight 276.13
http://www.lakesyn.com/html/e_262.html

For price inquiry, please send us email: sales@lakesyn.com

87199-17-5 | 4-Formylphenylboronic acid




Name: 4-Formylphenylboronic acid
Descriptions:
Product Number LS00096
CAS Number 87199-17-5
Product Name 4-Formylphenylboronic acid
Molecular Formula C7H7BO3
Formula Weight 149.94
http://www.lakesyn.com/html/e_1379.html

For price inquiry, please send us email: sales@lakesyn.com

87199-16-4 | 3-Formylphenylboronic acid




Name: 3-Formylphenylboronic acid
Descriptions:
Product Number LS00095
CAS Number 87199-16-4
Product Name 3-Formylphenylboronic acid
Molecular Formula C7H7BO3
Formula Weight 149.94
http://www.lakesyn.com/html/e_1378.html

For price inquiry, please send us email: sales@lakesyn.com

40138-16-7 | 2-Formylphenylboronic acid




Name: 2-Formylphenylboronic acid
Descriptions:
Product Number LS00094
CAS Number 40138-16-7
Product Name 2-Formylphenylboronic acid
Molecular Formula C7H7BO3
Formula Weight 149.94
http://www.lakesyn.com/html/e_1377.html

For price inquiry, please send us email: sales@lakesyn.com

Thursday, January 24, 2013

722544-51-6 | Barasertib (AZD1152-HQPA)




Name: Barasertib (AZD1152-HQPA)
Descriptions:
Product Number LS50096
CAS Number 722544-51-6
Product Name Barasertib (AZD1152-HQPA)
Molecular Formula C26H30FN7O3
Formula Weight 507.56
http://www.lakesyn.com/html/e_1621.html

For price inquiry, please send us email: sales@lakesyn.com

AZD1152-HQPA (Barasertib) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM.

166518-60-1 | Avasimibe (CI-1011)




Name: Avasimibe (CI-1011)
Descriptions:
Product Number LS50095
CAS Number 166518-60-1
Product Name Avasimibe (CI-1011)
Molecular Formula C29H43NO4S
Formula Weight 501.72
http://www.lakesyn.com/html/e_1620.html

For price inquiry, please send us email: sales@lakesyn.com

Avasimibe inhibits ACAT and CYP2C9 with IC50 of 3.3 μM and 2.9 μM, respectively.

844442-38-2 | AT7519




Name: AT7519
Descriptions:
Product Number LS50094
CAS Number 844442-38-2
Product Name AT7519
Molecular Formula C16H17Cl2N5O2
Formula Weight 382.24
http://www.lakesyn.com/html/e_1619.html

For price inquiry, please send us email: sales@lakesyn.com

AT7519 is a novel multi-CDK inhibitor for CDK1/cyclin B, CDK2/Cyclin A, CDK3/Cyclin E, CDK4/Cyclin D1, CDK5/p35 and CDK6/Cyclin D3 with IC50 of 210 nM, 47 nM, 360 nM, 100 nM, 13 nM and 170 nM, respectively.
CAS No. 844442-38-2, 902135-91-5 (HCl), 902135-89-1 (methanesulfonate)

69408-81-7 | Amonafide (NSC-308847, AS1413)




Name: Amonafide (NSC-308847, AS1413)
Descriptions:
Product Number LS50093
CAS Number 69408-81-7
Product Name Amonafide (NSC-308847, AS1413)
Molecular Formula C16H17N3O2
Formula Weight 283.33
http://www.lakesyn.com/html/e_1618.html

For price inquiry, please send us email: sales@lakesyn.com

Amonafide (NSC-308847) is a selective topoisomerase II inhibitor.
CAS No. 69408-81-7, 150091-68-2 (2HCl), 135882-21-2 (methanesulfonate)
Synonyms  AS1413, Xanafide, Quinamed

459868-92-9 | Rucaparib (AG-014699 , PF-01367338)




Name: Rucaparib (AG-014699 , PF-01367338)
Descriptions:
Product Number LS50092
CAS Number 459868-92-9
Product Name Rucaparib (AG-014699 , PF-01367338)
Molecular Formula C19H18FN3O.H3PO4
Formula Weight 421.36
http://www.lakesyn.com/html/e_1617.html

For price inquiry, please send us email: sales@lakesyn.com

Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM.
CAS No. 459868-92-9, 283173-50-2 (free base)

142340-99-6 | Adefovir Dipivoxil (Preveon, Hepsera)




Name: Adefovir Dipivoxil (Preveon, Hepsera)
Descriptions:
Product Number LS50091
CAS Number 142340-99-6
Product Name Adefovir Dipivoxil (Preveon, Hepsera)
Molecular Formula C20H32N5O8P
Formula Weight 501.47
http://www.lakesyn.com/html/e_1616.html

For price inquiry, please send us email: sales@lakesyn.com

Adefovir Dipivoxil(Preveon, Hepsera) works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. It is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease.
Synonyms Bis-POM PMEA, Preveon, Hepsera

Monday, January 21, 2013

153436-53-4 | AG-1478 (Tyrphostin AG-1478)




Name: AG-1478 (Tyrphostin AG-1478)
Descriptions:
Product Number LS50090
CAS Number 153436-53-4
Product Name AG-1478 (Tyrphostin AG-1478)
Molecular Formula C16H14ClN3O2
Formula Weight 315.75
http://www.lakesyn.com/html/e_1593.html

For price inquiry, please send us email: sales@lakesyn.com

AG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM.
CAS No. 153436-53-4, 170449-18-0 (HCl)

453562-69-1 | Motesanib Diphosphate (AMG-706)




Name: Motesanib Diphosphate (AMG-706)
Descriptions:
Product Number LS50089
CAS Number 453562-69-1
Product Name Motesanib Diphosphate (AMG-706)
Molecular Formula C22H23N5O.2H3PO4
Formula Weight 569.44
http://www.lakesyn.com/html/e_1592.html

For price inquiry, please send us email: sales@lakesyn.com

Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.
CAS No. 857876-30-3, 453562-69-1 (free base), 945716-97-2 (H2O)

943319-70-8 | Ponatinib (AP24534)




Name: Ponatinib (AP24534)
Descriptions:
Product Number LS50088
CAS Number 943319-70-8
Product Name Ponatinib (AP24534)
Molecular Formula C29H27F3N6O
Formula Weight 532.56
http://www.lakesyn.com/html/e_1591.html

For price inquiry, please send us email: sales@lakesyn.com

AP24534 is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively.
CAS No. 943319-70-8, 1232836-25-7 (3HCl)

170729-80-3 | Aprepitant (MK-0869, MK-869, L-754030, Emend)




Name: Aprepitant (MK-0869, MK-869, L-754030, Emend)
Descriptions:
Product Number LS50087
CAS Number 170729-80-3
Product Name Aprepitant (MK-0869, MK-869, L-754030, Emend)
Molecular Formula C23H21F7N4O3
Formula Weight 534.43
http://www.lakesyn.com/html/e_1590.html

For price inquiry, please send us email: sales@lakesyn.com

Aprepitant is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor. Aprepitant is used for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting.

229975-97-7 | Atazanavir sulfate(BMS-232632-05)




Name: Atazanavir sulfate(BMS-232632-05)
Descriptions:
Product Number LS50086
CAS Number 229975-97-7
Product Name Atazanavir sulfate(BMS-232632-05)
Molecular Formula C38H52N6O7.H2SO4
Formula Weight 802.93
http://www.lakesyn.com/html/e_1589.html

For price inquiry, please send us email: sales@lakesyn.com

Atazanavir sulfate(BMS-232632-05) is a sulfate salt form of atazanavir (BMS-232632) that is an highly potent HIV protease inhibitor with an EC50 and EC90 of 2.6~5.3 nM and 9~15 nM in cell culture. Atazanavir (BMS-232632) is generally more potent than the five currently approved HIV-1 Prt inhibitors. Atazanavir (BMS-232632) inhibited the proteolytic cleavage of the viral gag precursor p55 polyprotein in a dose-dependent manner, with a EC50 of approximately 47 nM. Furthermore, Atazanavir (BMS-232632) is highly selective for HIV-1 Prt and exhibits cytotoxicity only at concentrations 6,500- to 23,000-fold higher than that required for anti-HIV activity. Atazanavir (BMS-232632) may be an effective HIV-1 inhibitor that may be utilized in a variety of different drug combinations.
Synonyms  BMS-232632-05, Reyataz
CAS No. 229975-97-7 198904-31-3

602306-29-6 | AZD5438




Name: AZD5438
Descriptions:
Product Number LS50085
CAS Number 602306-29-6
Product Name AZD5438
Molecular Formula C18H21N5O2S
Formula Weight 371.46
http://www.lakesyn.com/html/e_1588.html

For price inquiry, please send us email: sales@lakesyn.com

AZD5438 is a potent inhibitor of CDK1, CDK2 and CDK9 with IC50 of 16 nM, 6 nM, and 20 nM, respectively.

Sunday, January 20, 2013

763113-22-0 | Olaparib (AZD2281, KU0059436)




Name: Olaparib (AZD2281, KU0059436)
Descriptions:
Product Number LS50084
CAS Number 763113-22-0
Product Name Olaparib (AZD2281, KU0059436)
Molecular Formula C24H23FN4O3
Formula Weight 434.46
http://www.lakesyn.com/html/e_1587.html

For price inquiry, please send us email: sales@lakesyn.com

Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1 and PARP2 with IC50 of 5 nM and 1 nM, respectively.
CAS No. 763113-22-0, 894104-70-2, 937799-91-2, 1021843-02-6
Synonyms KU-0059436

606143-52-6 | AZD6244 (Selumetinib, ARRY-142886)




Name: AZD6244 (Selumetinib, ARRY-142886)
Descriptions:
Product Number LS50083
CAS Number 606143-52-6
Product Name AZD6244 (Selumetinib, ARRY-142886)
Molecular Formula C17H15BrClFN4O3
Formula Weight 457.68
http://www.lakesyn.com/html/e_1586.html

For price inquiry, please send us email: sales@lakesyn.com

AZD6244 (Selumetinib, ARRY-142886) is highly potent to inhibit MEK1 with IC50 of 14 nM.
CAS No. 606143-52-6, 942275-12-9 (4-methylbenzenesulfonate)

1173900-33-8 | AZD6482




Name: AZD6482
Descriptions:
Product Number LS50082
CAS Number 1173900-33-8
Product Name AZD6482
Molecular Formula C22H24N4O4
Formula Weight 408.45
http://www.lakesyn.com/html/e_1585.html

For price inquiry, please send us email: sales@lakesyn.com

AZD6482 is an inhibitor of PI3Kβ with IC50 of 21 nM.

915019-65-7 | BEZ235 (NVP-BEZ235)




Name: BEZ235 (NVP-BEZ235)
Descriptions:
Product Number LS50081
CAS Number 915019-65-7
Product Name BEZ235 (NVP-BEZ235)
Molecular Formula C30H23N5O
Formula Weight 469.54
http://www.lakesyn.com/html/e_1584.html

For price inquiry, please send us email: sales@lakesyn.com

BEZ235 (NVP-BEZ235)is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively.
CAS No. 915019-65-7, 1028385-32-1 (4-methylbenzenesulfonate)

120410-24-4 | Biapenem




Name: Biapenem
Descriptions:
Product Number LS50080
CAS Number 120410-24-4
Product Name Biapenem
Molecular Formula C15H18N4O4S
Formula Weight 350.39
http://www.lakesyn.com/html/e_1583.html

For price inquiry, please send us email: sales@lakesyn.com

Biapenem is a carbapenem antibiotic. It has in vitro activity against anaerobes. Biapenem is a new parenteral carbapenem antibacterial agent with a broad spectrum of in vitro antibacterial activity encompassing many Gram-negative and Gram-positive aerobic and anaerobic bacteria, including species producing  β-lactamases.
Synonyms  L-627, LJC 10627

928326-83-4 | BIBF1120 (Vargatef)




Name: BIBF1120 (Vargatef)
Descriptions:
Product Number LS50079
CAS Number 928326-83-4
Product Name BIBF1120 (Vargatef)
Molecular Formula C31H33N5O4
Formula Weight 539.62
http://www.lakesyn.com/html/e_1582.html

For price inquiry, please send us email: sales@lakesyn.com

BIBF1120 (Vargatef) is a potent inhibitor of VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/5 nM/5 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.
CAS No. 656247-17-5, 790241-30-4 (methanesulfonate), 959761-73-0 (HCl)

Friday, January 18, 2013

439081-18-2 | Afatinib (BIBW2992)




Name: Afatinib (BIBW2992)
Descriptions:
Product Number LS50078
CAS Number 439081-18-2
Product Name Afatinib (BIBW2992)
Molecular Formula C24H25ClFN5O3
Formula Weight 485.94
http://www.lakesyn.com/html/e_1581.html

For price inquiry, please send us email: sales@lakesyn.com

BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.
CAS No. 439081-18-2, 936631-70-8 (Maleic acid), 1254955-21-9 (XHCl)

285983-48-4 | BIRB 796 (Doramapimod)




Name: BIRB 796 (Doramapimod)
Descriptions:
Product Number LS50077
CAS Number 285983-48-4
Product Name BIRB 796 (Doramapimod)
Molecular Formula C31H37N5O3
Formula Weight 527.66
http://www.lakesyn.com/html/e_1580.html

For price inquiry, please send us email: sales@lakesyn.com

BIRB 796 (Doramapimod) is a highly selective p38α MAPK inhibitor with Kd of 0.1 nM.
CAS No. 285983-48-4, 1283526-53-3 (HCl)

179324-69-7 | Bortezomib (Velcade)




Name: Bortezomib (Velcade)
Descriptions:
Product Number LS50076
CAS Number 179324-69-7
Product Name Bortezomib (Velcade)
Molecular Formula C19H25BN4O4
Formula Weight 384.24
http://www.lakesyn.com/html/e_1579.html

For price inquiry, please send us email: sales@lakesyn.com

Bortezomib (PS-341, MG-341, Velcade) is a potent proteasome inhibitor with Ki of 0.6 nM.